IscAlert™

IscAlert™ is a biomedical sensor system that measures the partial gas pressure of carbon dioxide (pCO2) in tissue local to sensor placement.

The problem today is that injury to most organs is detected too late. Unfortunately, existing detection solutions simply cannot provide the early, accurate and real time monitoring required by surgeons and healthcare organisations.

Ischemia is highly preventable if it can be detected early.

IscAlert™ is a ground-breaking and patented solution with a numbers of benefits

  • IscAlert™ is sensitive to pCO2 changes and can detect even small variations in a very early stage in tissues. PCO2 effectively signals when tissues are not receiving adequate oxygenation, regardless of the specific location or type of tissue affected. The rise in pCO2 levels is a reliable marker of metabolic distress, reflecting the accumulation of carbon dioxide in tissues due to compromised circulation and oxygen delivery.

  • IscAlert™ addresses a largely unmet medical need as a user friendly, fast and robust real-time monitoring device for increased pCO2 in tissue.

  • The IscAlert™ sensor is less than 1 mm in diameter in order to minimize tissue damage during insertion and for the in-dwelling duration. Clinical trials have shown no serious side effects using IscAlert™.

  • The IscAlert Introducer allows safe placement of the sensor with limited tissue damage and bleeding.

  • The IscAlert Sensor is sterile to prevent infection at the insertion site.

  • The IscAlert Sensor is biocompatible, which means it is suited for the tissue contact and not aggravate inflammation and allergic reactions.

Unlike other approaches, IscAlert™ provides continuous, real-time readings, detects early increases in pCO2 as can be experienced in cases of ischemia or hypoventilatory conditions,  and is easy and cost-effective to adopt.

Why measure pCO2?

The tissue pCO2 is a parameter which increases significantly during the early and reversible stages of ischemia. Monitoring of local tissue pCO2 provides the ability to identify the onset of ischemic events before irreversible injury occurs.

Why is ischemia important?

Ischemia is a restriction in blood supply – and thus oxygen (O2) delivery to tissues – leading to cellular stress and with potentially lethal consequences. Tissue hypoperfusion and ischemia in non-internal organs are involved in numerous pathological conditions and application scenarios. This includes scenarios with acute ischemia such as replantation surgery or reconstructive surgery, compartment syndrome, sepsis, or cardiogenic shock.

CriticAlert™

Sensocure is developing a new biomedical sensor system that could provide early warnings of circulatory and respiratory problems.

CriticAlert™ demonstrates potential applicability across diverse patient populations, particularly those admitted to hospitals with respiratory concerns. The system could be especially beneficial for individuals experiencing hypoxia or hypercapnia.

Its utility extends to various patient groups, encompassing those with chronic obstructive pulmonary disease (COPD), pneumonia), and other conditions that compromise respiratory function.

Additionally, CriticAlert™ might prove valuable for monitoring post-operative patients at risk of respiratory complications, as well as those in intensive care units requiring close respiratory surveillance.

The technology's versatility suggests it could enhance patient care and early intervention strategies across multiple medical scenarios involving respiratory distress.