The Product

IscAlert™ is a biomedical sensor system that measures the partial gas pressure of carbon dioxide (pCO2) in tissue local to sensor placement.

The problem today is that injury to most organs are detected too late. Unfortunately, existing detection solutions simply cannot provide the early, accurate and real time monitoring required by surgeons and healthcare organisations.

Ischemia is highly preventable if it can be detected early.

IscAlert™ is a ground-breaking and patented solution with a numbers of benefits

  • IscAlert™ detects ischemia at a very early stage by measuring the partial pressure of carbon dioxide in a tissue/organ (a universal indicator of insufficient blood supply).

  • IscAlert™ addresses a largely unmet medical need as a user friendly, fast and robust real-time monitoring device for increased pCO2 (partial gas pressure of carbon dioxide), which is an indication of ischemia.

  • The IscAlert™ sensor is less than 1 mm in diameter in order to minimize tissue damage during insertion and for the in-dwelling duration. Clinical trials have shown no serious side effects using IscAlert™.

  • The IscAlert™ system offers an opportunity for hospitals to improve patient outcome and save costly hospitalization care.

Why measure pCO2?

The tissue pCO2 is a parameter which increases significantly during the early and reversible stages of ischemia. Monitoring of local tissue pCO2 provides the ability to identify the onset of ischemic events before irreversible injury occurs.

Why is ischemia important?

Ischemia is a restriction in blood supply – and thus oxygen (O2) delivery to tissues – leading to cellular stress and with potentially lethal consequences. Tissue hypoperfusion and ischemia in non-internal organs are involved in numerous pathological conditions and application scenarios. This includes scenarios with acute ischemia such as replantation surgery or reconstructive surgery, compartment syndrome, sepsis, or cardiogenic shock.

IscAlert™

IscAlert™ is a proven miniature sensor technology easily placed into organs to accurately monitor tissue carbon dioxide (pCO2) in real time, giving clinicians ample time to take appropriate actions to prevent or minimize tissue/organ damage.

Unlike other approaches, IscAlert™ provides continuous, real-time readings, detects ischemia in all tissues, and is easy and cost-effective to adopt.